An evaluation of glycated haemoglobin eluting in zone 10 on capillary zone electrophoresis

Autor:	Pullon Beverley M.
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	capillary zone electrophoresis glycated haemoglobin hba1c zone 10 peaks Medical technology R855-855.5
Zdroj:	Journal of Laboratory Medicine, Vol 44, Iss 1, Pp 55-58 (2020)
Druh dokumentu:	article
ISSN:	2567-9430 2567-9449
DOI:	10.1515/labmed-2019-0136
Popis:	This is the first report of glycated haemoglobin (Hb) eluting in zone 10 on capillary zone electrophoresis (CZE). In an index case, the aberrant peak was picked up during routine haemoglobinopathy testing using CZE. Mass spectrometry (MS) revealed this aberrant peak to be glycated Hb. Prompted by this initial case, a study was undertaken and the results showed that there was a strong positive linear relationship (R2 = 0.774; ρ = 0.88) between the level of glycated Hb peak eluting in zone 10 and the HbA1c value. Furthermore, all samples with an HbA1c of 54 mmol/mol or greater had an HbA1c peak eluting in zone 10.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/12b59c5373434fdab7ffa3661058b52e Zobrazit plný text záznamu View record in DOAJ