Potential of high dimensional radiomic features to assess blood components in intraaortic vessels in non-contrast CT scans

Autor: Scherwin Mahmoudi, Simon S. Martin, Jörg Ackermann, Yauheniya Zhdanovich, Ina Koch, Thomas J. Vogl, Moritz H. Albrecht, Lukas Lenga, Simon Bernatz
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Medical Imaging, Vol 21, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 1471-2342
DOI: 10.1186/s12880-021-00654-9
Popis: Abstract Background To assess the potential of radiomic features to quantify components of blood in intraaortic vessels to non-invasively predict moderate-to-severe anemia in non-contrast enhanced CT scans. Methods One hundred patients (median age, 69 years; range, 19–94 years) who received CT scans of the thoracolumbar spine and blood-testing for hemoglobin and hematocrit levels ± 24 h between 08/2018 and 11/2019 were retrospectively included. Intraaortic blood was segmented using a spherical volume of interest of 1 cm diameter with consecutive radiomic analysis applying PyRadiomics software. Feature selection was performed applying analysis of correlation and collinearity. The final feature set was obtained to differentiate moderate-to-severe anemia. Random forest machine learning was applied and predictive performance was assessed. A decision-tree was obtained to propose a cut-off value of CT Hounsfield units (HU). Results High correlation with hemoglobin and hematocrit levels was shown for first-order radiomic features (p
Databáze: Directory of Open Access Journals