Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis
Autor: | Rebecca A Kuennen, Reynell Harder Smith, Thomas F Mauger, et al |
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Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: | |
Zdroj: | Clinical Ophthalmology, Vol 2010, Iss default, Pp 1145-1149 (2010) |
Druh dokumentu: | article |
ISSN: | 1177-5467 1177-5483 |
Popis: | Rebecca A Kuennen, Reynell Harder Smith, Thomas F Mauger, Elson CraigDepartment of Ophthalmology, The Ohio State University, Columbus, Ohio, USAPurpose: To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine.Methods: A case of advanced Acanthamoeba sclerokeratitis was resistant to conventional therapy and was treated with intravenous pentamidine. The eye was later removed due to incapacitating pain.Results: The eye showed Acanthamoeba organisms within the cornea and evidence of acute and chronic inflammation throughout the remainder of the eye. The patient has survived without orbital recurrence for 2 years.Conclusions: This case demonstrates late inflammation with active Acanthameoba keratitis following systemic pentamidine therapy.Keywords: keratitis, scleritis |
Databáze: | Directory of Open Access Journals |
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