Enucleation following treatment with intravenous pentamidine for Acanthamoeba sclerokeratitis

Autor: Rebecca A Kuennen, Reynell Harder Smith, Thomas F Mauger, et al
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Clinical Ophthalmology, Vol 2010, Iss default, Pp 1145-1149 (2010)
Druh dokumentu: article
ISSN: 1177-5467
1177-5483
Popis: Rebecca A Kuennen, Reynell Harder Smith, Thomas F Mauger, Elson CraigDepartment of Ophthalmology, The Ohio State University, Columbus, Ohio, USAPurpose: To describe the course and outcome of treatment of advanced Acanthamoeba sclerokeratitis with intravenous pentamidine.Methods: A case of advanced Acanthamoeba sclerokeratitis was resistant to conventional therapy and was treated with intravenous pentamidine. The eye was later removed due to incapacitating pain.Results: The eye showed Acanthamoeba organisms within the cornea and evidence of acute and chronic inflammation throughout the remainder of the eye. The patient has survived without orbital recurrence for 2 years.Conclusions: This case demonstrates late inflammation with active Acanthameoba keratitis following systemic pentamidine therapy.Keywords: keratitis, scleritis
Databáze: Directory of Open Access Journals