Characteristics and Application Value of Handwriting in Elderly Patients with Mild Cognitive Impairment

Autor: WEI Zhuqin, ZHANG Ruoyu, ZHANG Chen, SU Liming, HUANG Cheng, ZHANG Junwei, QIAN Mincai, QI Hengnian, WANG Lina
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: Zhongguo quanke yixue, Vol 26, Iss 10, Pp 1224-1233 (2023)
Druh dokumentu: article
ISSN: 1007-9572
DOI: 10.12114/j.issn.1007-9572.2022.0729
Popis: Background Handwriting synthesis techniques have been extensively studied in the detection of cognitive impairment in dementia and Parkinson's disease. But handwriting characteristics in older adults with mild cognitive impairment (MCI) still need to be studied further. Objective To explore the differences between the handwriting characteristics of elderly patients with MCI and normal elderly people, and to assess the value of handwriting features in MCI screening. Methods By use of convenience sampling, 33 older adults with MCI were recruited from Huzhou communities from January to April 2022 (observation group), and were compared to age-, sex- and education level-matched 43 community-living older adults with normal cognitive function (control group). The General Information Questionnaire, the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment-Basic (MoCA-B), the Activity of Daily Living Scale (ADL), and the 15-item Geriatric Depression Scale (GDS-15) were used to survey subjects. Subjects were invited to complete six handwriting tasks (four are Chinese characters tasks and the other two are graphical drawing tasks) using a dot matrix digital pen to collect their kinematic parameters of handwriting. The classification accuracy, sensitivity and specificity of handwriting characteristics for the diagnosis of MCI were analyzed by discriminant analysis and receiver operating characteristic (ROC) curve, and predictive values of different schemes for MCI were analyzed. Results Compared with the control group, the observation group had higher average pressure in writing (Z=-2.122, P=0.034), longer time in air (Z=-4.302, P
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