Seroprevalence of cytomegalovirus and its coinfection with Epstein-Barr virus in adult residents from Manaus: a population-based study

Autor: Gustavo Magno Baldin Tiguman, Laura Beatrice Poll, Carlos Eduardo de Castro Alves, Gemilson Soares Pontes, Marcus Tolentino Silva, Tais Freire Galvao
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 53 (2020)
Druh dokumentu: article
ISSN: 1678-9849
0037-8682
DOI: 10.1590/0037-8682-0363-2019
Popis: Abstract INTRODUCTION: This study assessed the seroprevalence of cytomegalovirus, associated factors, and Epstein-Barr virus coinfection among adult residents of Manaus. METHODS: Using a cross-sectional study design, we collected blood samples from 136 individuals in a household survey in 2016. Prevalence ratios were calculated using Poisson regression. RESULTS: Cytomegalovirus and Epstein-Barr virus seroprevalences were 67.6% (95% CI: 9.7-75.6%) and 97.8% (95% CI: 95.3-100.0%), respectively. Coinfection was observed in 66.2% (95% CI: 58.1-74.2%) of participants. Bivariate analysis showed no statistical association. CONCLUSIONS: Seroprevalences were high among participants and approximately 7 out of 10 individuals had cytomegalovirus and Epstein-Barr virus coinfection.
Databáze: Directory of Open Access Journals