Association between alopecia areata and COVID-19: A systematic reviewCapsule Summary

Autor: Rachel E. Christensen, BS, Mohammad Jafferany, MD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: JAAD International, Vol 7, Iss , Pp 57-61 (2022)
Druh dokumentu: article
ISSN: 2666-3287
DOI: 10.1016/j.jdin.2022.02.002
Popis: Background: COVID-19 may play a role in various immune-related dermatologic conditions. The relationship between COVID-19 and alopecia areata remains unclear. Objective: To review the existing literature for clinical studies and reports investigating the association between new-onset alopecia areata or the exacerbation of preexisting alopecia areata following infection with SARS-CoV-2. Methods: A systematic review of the literature was performed using PubMed, Embase, and MEDLINE databases from inception to October 2021. Included articles assessed alopecia areata following infection with SARS-CoV-2. Results: Of 402 total articles, 9 were identified as meeting the inclusion criteria. Six articles described case reports of 7 patients with new-onset alopecia areata following confirmed infection with SARS-CoV-2, and 3 articles reported on alopecia areata recurrence or exacerbation following SARS-CoV-2 infection in patients with preexisting disease. Studies investigating the exacerbation or recurrence of alopecia areata following infection reported mixed findings. Limitations: A majority of the included studies were case reports. The heterogeneity of articles precluded data synthesis. Conclusion: Alopecia areata may be a dermatologic manifestation of COVID-19, with cases most often appearing 1 to 2 months following infection. Additional research is necessary to better elucidate the relationship and draw conclusions.
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