Evaluation of Pro‐BNP biomarker in heart failure patients and its relationship with complete blood count parameters: A case–control study

Autor: Ekhlas Torfi, Seyed S. Bahreiny, Najmaldin Saki, Reyhane Khademi, Ehsan Sarbazjoda, Inas A. Nezhad, Mojtaba Aghaei
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Health Science Reports, Vol 7, Iss 9, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2398-8835
DOI: 10.1002/hsr2.70083
Popis: Abstract Background and aims Heart failure (HF) is a growing global health concern. N‐terminal prohormone of brain natriuretic peptide (NT‐pro‐BNP) is an established biomarker for ventricular dysfunction in heart failure (HF). This case–control study examined the relationship between brain natriuretic peptide (Pro‐BNP) levels and complete blood count (CBC) parameters in HF patients and healthy controls, exploring the utility of CBC as a supplementary diagnostic tool for HF. Methods The study included 89 participants, divided into 42 HF patients with diagnosed HF (patient group) and 47 healthy individuals (control group). Pro‐BNP levels were measured alongside a comprehensive CBC panel, including parameters such as white blood cell count, hemoglobin levels, and platelet count. Demographic, clinical characteristics, and CBC parameters were compared between the two groups, with statistical analyses performed to identify any significant associations. Results The analysis demonstrated that HF patients had significantly higher Pro‐BNP levels than the control subjects, indicating a strong association between Pro‐BNP levels and HF (1052.65 [196.56] vs. 2500.34 [1105.90], p
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