Serum Neuropeptide Y and Leptin Levels compared between Non-pregnant and Pregnant Women in Overall, Non-obese, and Obese Subjects

Autor: Chantacha Sitticharoon, M.D., Ph.D., Roongrit Klinjampa, M.Sc., Xaynaly Souvannavong-Vilivong, M.Sc., Saimai Chatree, M.Sc., Peerada Boonpuan, M.Sc., Chanakarn Sripong, M.Sc., Nay Chi Nway, MBBS., M.Sc., Tripop Lertbunnaphong, M.D.
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Siriraj Medical Journal, Vol 70, Iss 3, Pp 204-212 (2018)
Druh dokumentu: article
ISSN: 2228-8082
DOI: 10.14456/smj.2018.34
Popis: Objective: The primary objective of this study was to compare serum NPY and leptin levels between non-pregnant and pregnant women in overall, non-obese, and obese subjects. The secondary objective was to compare these peptides between non-obese and obese pregnant women. Methods: Fasting venous blood was collected from non-pregnant women before open abdominal surgery and from pregnant women when admitted to the delivery room during the latent phase of labor. Results: There were 12 non-obese and 14 obese subjects in the non-pregnant group and 9 non-obese and 30 obese subjects in the pregnant group. Systolic blood pressure (SBP) was comparable, but heart rate (HR) was higher in pregnant compared to non-pregnant women. Mean±S.E.M serum NPY levels were lower in the pregnant than in the non-pregnant group in overall (0.54±0.02 and 1.34±0.08, respectively), non-obese (0.53±0.05 and 1.23±0.14, respectively), and obese (0.54±0.03 and 1.43±0.09, respectively) subjects (p
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