Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments

Autor: Kartik Kumar, Charles L. Daley, David E. Griffith, Michael R. Loebinger
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: European Respiratory Review, Vol 31, Iss 163 (2022)
Druh dokumentu: article
ISSN: 0905-9180
1600-0617
16000617
DOI: 10.1183/16000617.0212-2021
Popis: Nontuberculous mycobacterial pulmonary disease (NTM-PD) remains a challenging condition to diagnose and treat effectively. Treatment of NTM-PD is prolonged, frequently associated with adverse effects and has variable success. In this review, we consider the factors influencing clinicians when treating NTM-PD and discuss outcomes from key studies on the pharmacological management of Mycobacterium avium complex pulmonary disease and M. abscessus pulmonary disease. We highlight issues relating to treatment-related toxicity and provide an overview of repurposed and emerging therapies for NTM-PD.
Databáze: Directory of Open Access Journals