Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments
Autor: | Kartik Kumar, Charles L. Daley, David E. Griffith, Michael R. Loebinger |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | European Respiratory Review, Vol 31, Iss 163 (2022) |
Druh dokumentu: | article |
ISSN: | 0905-9180 1600-0617 16000617 |
DOI: | 10.1183/16000617.0212-2021 |
Popis: | Nontuberculous mycobacterial pulmonary disease (NTM-PD) remains a challenging condition to diagnose and treat effectively. Treatment of NTM-PD is prolonged, frequently associated with adverse effects and has variable success. In this review, we consider the factors influencing clinicians when treating NTM-PD and discuss outcomes from key studies on the pharmacological management of Mycobacterium avium complex pulmonary disease and M. abscessus pulmonary disease. We highlight issues relating to treatment-related toxicity and provide an overview of repurposed and emerging therapies for NTM-PD. |
Databáze: | Directory of Open Access Journals |
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