Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

Autor: Catherine S. Storm, Demis A. Kia, Mona M. Almramhi, Sara Bandres-Ciga, Chris Finan, International Parkinson’s Disease Genomics Consortium (IPDGC), Aroon D. Hingorani, Nicholas W. Wood
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Druh dokumentu: article
ISSN: 2041-1723
12208590
DOI: 10.1038/s41467-021-26280-1
Popis: There is currently no disease-modifying treatment for Parkinson’s disease, a common neurodegenerative disorder. Here, the authors use genetic variation associated with gene and protein expression to find putative drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome.
Databáze: Directory of Open Access Journals
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