TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription

Autor: Emmanuel Compe, Carlos M. Genes, Cathy Braun, Frederic Coin, Jean-Marc Egly
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-10131-1
Popis: The general transcription factors TFIIE and TFIIH assemble at the transcription start site with RNA Polymerase II. Here the authors provide evidence that the TFIIEα and TFIIEβ subunits anchor the TFIIH kinase module within the preinitiation complex before their release during transcription.
Databáze: Directory of Open Access Journals