Estradiol decreases iodide uptake by rat thyroid follicular FRTL-5 cells

Autor:	Furlanetto T.W., Nunes Jr. R.B., Sopelsa A.M.I., Maciel R.M.B.
Jazyk:	angličtina
Rok vydání:	2001
Předmět:	iodide uptake estradiol thyroid follicular cells Medicine (General) R5-920 Biology (General) QH301-705.5
Zdroj:	Brazilian Journal of Medical and Biological Research, Vol 34, Iss 2, Pp 259-263 (2001)
Druh dokumentu:	article
ISSN:	0100-879X 0034-7310
Popis:	Estradiol has well-known indirect effects on the thyroid. A direct effect of estradiol on thyroid follicular cells, increasing cell growth and reducing the expression of the sodium-iodide symporter gene, has been recently reported. The aim of the present investigation was to study the effect of estradiol on iodide uptake by thyroid follicular cells, using FRTL-5 cells as a model. Estradiol decreased basal iodide uptake by FRTL-5 cells from control levels of 2.490 ± 0.370 to 2.085 ± 0.364 pmol I-/µg DNA at 1 ng/ml (P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/1214cf3af05d478f92d05c3dea7ce322 Zobrazit plný text záznamu View record in DOAJ