Differences in maternal and neonatal cardiometabolic markers and placenta status by foetal sex. The GESTAFIT project

Autor: Virginia A Aparicio, Laura Baena-García, Marta Flor-Alemany, Luis J Martínez-González, Alfonso Varela-López, Cristina Sánchez, José L Quiles
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Women's Health, Vol 18 (2022)
Druh dokumentu: article
ISSN: 1745-5065
17455057
DOI: 10.1177/17455057221117976
Popis: Aims: To explore the differences in some maternal-neonatal metabolic markers and placenta status by foetal sex. Methods: One hundred thirty-nine Caucasian pregnant women from the GESTAFIT project and their new-borns were included in the present cross-sectional study. Serum cardiometabolic markers (i.e. lipid and glycaemic profile and uric acid) were analysed at late pregnancy and at birth. In placenta, telomeres length, proportion of deleted mitochondrial-DNA and mitochondrial-DNA density, some minerals and interleukin 8, epidermal growth factor, fibroblast growth factor-2 and vascular endothelial growth factor were measured. The study was run between November 2015 and April 2018. Results: Mothers carrying a male showed higher serum triglycerides than mothers carrying a female at late pregnancy ( p
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