B Lymphocytes, but Not Dendritic Cells, Efficiently HIV-1 Trans Infect Naive CD4 + T Cells: Implications for the Viral Reservoir

Autor: Abigail Gerberick, Diana C. DeLucia, Paolo Piazza, Mounia Alaoui-El-Azher, Charles R. Rinaldo, Nicolas Sluis-Cremer, Giovanna Rappocciolo
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mBio, Vol 12, Iss 2 (2021)
Druh dokumentu: article
ISSN: 2150-7511
DOI: 10.1128/mBio.02998-20
Popis: The latent human immunodeficiency virus type 1 (HIV-1) reservoir in persons on antiretroviral therapy (ART) represents a major barrier to a cure. Although most studies have focused on the HIV-1 reservoir in the memory T cell subset, replication-competent HIV-1 has been isolated from T NnegN
Databáze: Directory of Open Access Journals