A cluster randomized controlled trial of an online psychoeducational intervention for people with a family history of depression

Autor: Llewellyn Mills, Bettina Meiser, Raghib Ahmad, Peter R. Schofield, Michelle Peate, Charlene Levitan, Lyndal Trevena, Kristine Barlow-Stewart, Timothy Dobbins, Helen Christensen, Kerry A. Sherman, Kate Dunlop, Philip B. Mitchell
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Psychiatry, Vol 19, Iss 1, Pp 1-11 (2019)
Druh dokumentu: article
ISSN: 1471-244X
DOI: 10.1186/s12888-018-1994-2
Popis: Abstract Background People with a family history of major depressive disorder (MDD) or bipolar disorder (BD) report specific psychoeducational needs that are unmet by existing online interventions. This trial aimed to test whether an interactive website for people at familial risk for depression (intervention) would improve intention to adopt, or actual adoption of, depression prevention strategies (primary outcome) and a range of secondary outcome measures. Methods In this cluster randomised trial, primary care practises were randomised to either provide the link to the intervention or the control website. Primary health care attendees were invited by letter to opt into this study if they had at least one first-degree relative with MDD or BD and were asked to complete online questionnaires at baseline and 2-week follow-up. Results Twenty general practices were a randomized, and 202 eligible patients completed both questionnaires. Thirty-nine (19.3%) of participants were male and 163 (80.7%) female. At follow-up, compared to controls, the intervention group: (i) were more likely to intend to undergo, or to have actually undergone, psychological therapies (OR = 5.83, 95% CI: 1.58–21.47, p = .008); (ii) had better knowledge of depression risk factors and prevention strategies (mean difference = 0.47, 95% CI: 0.05–0.88, p = .029); and (iii) were more likely to accurately estimate their lifetime risk of developing BD (mean difference = 11.2, 95% CI: -16.52– -5.73, p
Databáze: Directory of Open Access Journals
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