Serostatus of echovirus 11, coxsackievirus B3 and enterovirus D68 in cord blood: The implication of severe newborn enterovirus infection

Autor: Ya-Li Hu, Shin-Yu Lin, Chien-Nan Lee, Jin-Chung Shih, Ai-Ling Cheng, Shun-Hua Chen, Luan-Yin Chang, Chi-Tai Fang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Microbiology, Immunology and Infection, Vol 56, Iss 4, Pp 766-771 (2023)
Druh dokumentu: article
ISSN: 1684-1182
DOI: 10.1016/j.jmii.2023.05.004
Popis: Background: Maternal transplacental antibody is an important origins of passive immunity against neonatal enterovirus infection. Echovirus 11 (E11) and coxsackievirus B3 (CVB3) are important types causing neonatal infections. There were few investigations of enterovirus D68 (EVD68) infection in neonates. We aimed to investigate the serostatus of cord blood for these three enteroviruses and evaluate the factors associated with seropositivity. Methods: We enrolled 222 parturient (gestational age 34–42 weeks) women aged 20–46 years old between January and October 2021. All participants underwent questionnaire investigation and we collected the cord blood to measure the neutralization antibodies against E11, CVB3 and EVD68. Results: The cord blood seropositive rates were 18% (41/222), 60% (134/232) and 95% (211/222) for E11, CVB3 and EVD68, respectively (p
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