Virological evidence of the impact of non-pharmaceutical interventions against COVID-19 in Ecuador, a resource-limited setting

Autor: Andres Moreira-Soto, Alfredo Bruno, Doménica de Mora, Michelle Paez, Jimmy Garces, Ben Wulf, Anna-Lena Sander, Maritza Olmedo, Maria José Basantes Mantilla, Manuel Gonzalez Gonzalez, Solon Alberto Orlando, Silvia Salgado Cisneros, Juan Carlos Zevallos, Jan Felix Drexler
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Druh dokumentu: article
ISSN: 22221751
2222-1751
DOI: 10.1080/22221751.2023.2259001
Popis: Ecuador had substantial COVID-19-mortality during 2020 despite early implementation of non-pharmaceutical interventions (NPIs). Resource-limited settings like Ecuador have high proportions of informal labour which entail high human mobility, questioning efficacy of NPIs. We performed a retrospective observational study in Ecuador’s national reference laboratory for viral respiratory infections during March 2020–February 2021 using stored respiratory specimens from 1950 patients, corresponding to 2.3% of all samples analysed within the Ecuadorian national surveillance system per week. During 2020, detection of SARS-CoV-2 (Pearson correlation; r = −0.74; p = 0.01) and other respiratory viruses (Pearson correlation; r = −0.68; p = 0.02) by real-time RT–PCR correlated negatively with NPIs stringency. Among respiratory viruses, adenoviruses (Fisher’s exact-test; p = 0.026), parainfluenzaviruses (p = 0.04), enteroviruses (p
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