Efficacy of oral viscous budesonide to reduce dilation treatment after esophageal atresia repair: a retrospective study

Autor: Cosimo Ruggiero, Giusy Russo, Denis Cozzi, Silvia Ceccanti, Chiara Scanziani, Danila Volpe, Paola Papoff, Mattia Spatuzzo, Vasiliki Spyropoulou, Salvatore Oliva
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Gastroenterology, Vol 3 (2024)
Druh dokumentu: article
ISSN: 2813-1169
DOI: 10.3389/fgstr.2024.1404292
Popis: IntroductionAnastomotic stricture is a common complication following esophageal atresia (EA) repair, substantially affecting the patient’s quality of life (QoL). Multiple dilations are often required to maintain the appropriate diameter of the esophagus, leading to ongoing challenges. The aim of this study is to assess the efficacy of oral viscous budesonide (OVB) in prolonging the time between symptom recurrence and subsequent dilation.MethodsWe carried out a retrospective single-center study for pediatric patients (0–18 years) who had undergone recurrent esophageal dilations (≥3) following EA repair and initiated treatment with OVB (1 mg/day
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