Acute organophosphorus toxicity in a regional hospital in Johannesburg, South Africa: A retrospective chart review

Autor: Vanessa Khonje, Jedd Hart, Jakus Venter, Saisha Deonarain, Saul Grossberg
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: African Journal of Emergency Medicine, Vol 13, Iss 2, Pp 104-108 (2023)
Druh dokumentu: article
ISSN: 2211-419X
DOI: 10.1016/j.afjem.2023.04.002
Popis: Introduction: Intentional and accidental organophosphorus exposures pose a significant healthcare-related burden on South African communities. This study will review the demographics, characteristics and clinical course of patients presenting with features of acute organophosphorus toxicity to a regional Emergency Centre in Johannesburg, South Africa. Methods: This was a retrospective chart review of all patients treated for possible acute organophosphorus toxicity from January 2020 to August 2021. Results: A total of 205 patients were identified of which 134 patients were included in the study. The median age was 26 years with a male predominance (male= 56%, female=44%). 109 patients (81.3%) survived, 18 patients (13.4%) demised and the outcome of 7 patients (5.2%) was unknown. The median hospital length of stay was 8 days, (IQR= 5-13 days), and the longest hospital stay was 37 days in ICU. Atropinisation dose was significantly higher for intubated patients (median=140.0mg; IQR=90mg-219.5mg) compared to patients who were not intubated (median=60mg; IQR=20.5mg-120mg, p
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