| Autor: |
V. P. Sergiev |
| Jazyk: |
ruština |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Журнал инфектологии, Vol 4, Iss 4, Pp 97-104 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
2072-6732 |
| DOI: |
10.22625/2072-6732-2012-4-4-97-104 |
| Popis: |
Longitudinal co-evolution of human beings and pathogens resulted in polymorphism of Homo sapiens. CCR5Δ32 HIV-resistance allele is the exception to the rules. Recent origin of HIV-1 in Africa contradicted with the appearance of CCR5Δ32 allele in Northern Europe in previous ages.The author proposed non-contradictory theory of primary appearance of ancient HIV-1 in the Northern Europe 5-7 thousand years ago. The primary epidemics of HIV-infection had been stopped by the appearance of CCR5Δ32 mutation among the affected population. Re-emergence of HIV-1 nowadays resulted by the penetration of hibernated HIV-1 into population of drug addicts and homosexual men. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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