Quantification of myocardial strain in patients with isolated left ventricular non-compaction and healthy subjects using deformable registration algorithm: comparison with feature tracking

Autor: Jia Liu, Yumin Li, Yue Cui, Yukun Cao, Sheng Yao, Xiaoyue Zhou, Jens Wetzl, Wenjuan Zeng, Heshui Shi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-9 (2020)
Druh dokumentu: article
ISSN: 1471-2261
DOI: 10.1186/s12872-020-01668-x
Popis: Abstract Background Systolic dysfunction of the left ventricle is frequently associated with isolated left ventricular non-compaction (iLVNC). Clinically, the ejection fraction (EF) is the primary index of cardiac function. However, changes of EF usually occur later in the disease course. Feature tracking (FT) and deformable registration algorithm (DRA) have become appealing techniques for myocardial strain assessment. Methods Thirty patients with iLVNC (36.7 ± 13.3 years old) and fifty healthy volunteers (42.3 ± 13.6 years old) underwent cardiovascular magnetic resonance (CMR) examination on a 1.5 T MR scanner. Strain values in the radial, circumferential, longitudinal directions were analyzed based on the short-axis and long-axis cine images using FT and DRA methods. The iLVNC patients were further divided based on the ejection fraction, into EF ≥ 50% group (n = 11) and EF
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