Current status of clinical application of immunotherapy in the treatment of glioma: A narrative review

Autor:	Qiuzi Chen, Peng Ren, Guohao Huang, Zuoxin Zhang, Jean-Philippe Hugnot, Shengqing Lv
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	chimeric antigen receptor-t-cell glioma immune checkpoint inhibitor oncolytic virus tumor vaccine Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Glioma, Vol 6, Iss 1, Pp 3-8 (2023)
Druh dokumentu:	article
ISSN:	2589-6113 2589-6121
DOI:	10.4103/glioma.glioma_2_23
Popis:	Glioma is a common type of brain tumor. Current treatment for glioma includes surgical resection, radiotherapy, chemotherapy, and tumor-treating fields. The application of immunotherapy to treat glioma is still far from satisfactory in the clinic. Here, we review the mechanisms of immunotherapy for glioma (including immune checkpoint inhibitor, chimeric antigen receptor-T-cell, tumor vaccine, and oncolytic virus) and the results of completed clinical trials, and will discuss the current status of immunotherapy and possible future directions.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/11c313c683024888b2837526c053875e Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF