Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkers

Autor: Kenneth E. Westerman, Timothy D. Majarian, Franco Giulianini, Dong-Keun Jang, Jenkai Miao, Jose C. Florez, Han Chen, Daniel I. Chasman, Miriam S. Udler, Alisa K. Manning, Joanne B. Cole
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-31625-5
Popis: Understanding how our genes interact with the environment is critical to improving health. Using a large-scale discovery pipeline, here the authors investigate synergies between genetic variants and a broad range of environmental factors impacting cardiometabolic health.
Databáze: Directory of Open Access Journals