Synthesis and structure of vanillin azomethines

Autor: Jasmina M. Jovanović, Sandra S. Konstantinović, Budimir V. Konstantinović
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Chemical Industry and Chemical Engineering Quarterly, Vol 15, Iss 4, Pp 279-281 (2009)
Druh dokumentu: article
ISSN: 1451-9372
Popis: Vanillin is most prominent as the principal flavor and aroma compound in vanilla. Vanillin has been used as a chemical intermediate in the production of pharmaceuticals and other fine chemicals.The two intermediates, assigned as intermediates I and II, were prepared by using vanillin and 1-butylbromide or 2-chloroacetic acid, respectively. The condensation of intermediates with 2,3- -diaminopyridine gave azomethines. Their structure was established by using elemental microanalysis, as well as UV/Vis, FTIR and 1H-NMR spectra. Synthesized compounds were tested for their antifungal activity against Candida albicans, Candida lipolytica and Sacharomyces cerevisiae.
Databáze: Directory of Open Access Journals
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