| Autor: |
Joel M. J. Tan, Monica E. Garner, James M. Regeimbal, Catherine J. Greene, Jorge D. Rojas Márquez, Dustin A. Ammendolia, Adam R. R. McCluggage, Taoyingnan Li, Katherine J. Wu, Marija Cemma, Philip P. Ostrowski, Brian Raught, Michael S. Diamond, Sergio Grinstein, Robin M. Yates, Darren E. Higgins, John H. Brumell |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-24982-0 |
| Popis: |
Interferon (IFN) is an important component of antiviral immunity, but can also be exploited by bacteria for immune evasion. Here the authors show that Listeria monocytogenes (Lm) induces type I IFN to suppress the degradation of Lm virulence proteins, ActA and LLO, and promote Lm infection in an IFITM3-dependent manner, thereby hinting at a potential target for antimicrobial therapy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Full text from SpringerLink