Feasibility study of laser-driven neutron sources for pharmaceutical applications
| Autor: | Takato Mori, Akifumi Yogo, Yasunobu Arikawa, Takehito Hayakawa, Seyed R. Mirfayzi, Zechen Lan, Tianyun Wei, Yuki Abe, Mitsuo Nakai, Kunioki Mima, Hiroaki Nishimura, Shinsuke Fujioka, Ryosuke Kodama |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | High Power Laser Science and Engineering, Vol 11 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2095-4719 2052-3289 |
| DOI: | 10.1017/hpl.2023.4 |
| Popis: | We predict the production yield of a medical radioisotope ${}^{67}$ Cu using ${}^{67}$ Zn(n, p) ${}^{67}$ Cu and ${}^{68}$ Zn(n, pn) ${}^{67}$ Cu reactions with fast neutrons provided from laser-driven neutron sources. The neutrons were generated by the p+ ${}^9\mathrm{Be}$ and d+ ${}^9$ Be reactions with high-energy ions accelerated by laser–plasma interaction. We evaluated the yield to be (3.3 $\pm$ 0.5) $\times$ 10 ${}^5$ atoms for ${}^{67}$ Cu, corresponding to a radioactivity of 1.0 $\pm$ 0.2 Bq, for a Zn foil sample with a single laser shot. Using a simulation with this result, we estimated ${}^{67}$ Cu production with a high-frequency laser. The result suggests that it is possible to generate ${}^{67}$ Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital. |
| Databáze: | Directory of Open Access Journals |
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