Autoimmune pulmonary alveolar proteinosis presenting as localized multifocal GGOs: A case report

Autor: Koichi Honda, MD, Hirofumi Koike, MD, Shin Tsutsui, MD, Ryo Toya, MD, Keitaro Matsumoto, MD, Shinji Okano, MD, Hirokazu Taniguchi, MD, Kazuto Ashizawa, MD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Radiology Case Reports, Vol 19, Iss 12, Pp 6072-6075 (2024)
Druh dokumentu: article
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2024.08.097
Popis: Pulmonary alveolar proteinosis (PAP) is a rare disease, which is characterized by the alveolar accumulation of surfactant. A crazy-paving appearance on chest thin-section computed tomography (TSCT) is a characteristic feature of this disease. We report an unusual case of PAP, which presented as multiple localized ground glass opacites (GGOs) on TSCT in an 80-year-old female. As one of these lesions at the apex of the right lung increased in size, it was suspected to be a pulmonary adenocarcinoma. However, the others became smaller during the follow-up period. Right upper lobectomy was performed, and PAP was histologically diagnosed. In cases exhibiting multiple localized GGOs, PAP should be considered, even if GGOs with a crazy-paving-like appearance are distributed in a lobular rather than diffuse manner.
Databáze: Directory of Open Access Journals