Encapsulation of Imazalil in HKUST-1 with Versatile Antimicrobial Activity

Autor: Hongqiang Dong, Yuke He, Chen Fan, Zhongqiang Zhu, Chunrong Zhang, Xinju Liu, Kun Qian, Tao Tang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nanomaterials, Vol 12, Iss 21, p 3879 (2022)
Druh dokumentu: article
ISSN: 2079-4991
DOI: 10.3390/nano12213879
Popis: Based on high surface areas, adjustable porosity and microbicide activity, metal-organic frameworks (MOFs) HKUST-1 are widely used as drug release carriers for their slow degradation characteristics under slightly acidic conditions. In this work, porous HKUST-1 was reacted rapidly by cholinium salt (as the deprotonation agent and template) in an aqueous solution at room temperature. A novel antimicrobial system based on an imazalil encapsulated metal organic framework (imazalil IL-3@HKUST-1) was established. Imazalil IL-3@HKUST-1 could achieve synergism in inhibiting pathogenic fungi and bacteria. Moreover, six days after treatment, the slow and constant release of imazalil from imazalil IL@HKUST-1 exhibited better sustainability and microbicidal activity than imazalil. We believe that the method may provide a new strategy for related plant diseases caused by bacteria or fungi.
Databáze: Directory of Open Access Journals