Epizootiological investigation of equine herpesvirus type 1 infection among Japanese racehorses before and after the replacement of an inactivated vaccine with a modified live vaccine

Autor: Hiroshi Bannai, Koji Tsujimura, Manabu Nemoto, Minoru Ohta, Takashi Yamanaka, Hiroshi Kokado, Tomio Matsumura
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Veterinary Research, Vol 15, Iss 1, Pp 1-10 (2019)
Druh dokumentu: article
ISSN: 1746-6148
DOI: 10.1186/s12917-019-2036-0
Popis: Abstract Background Equine herpesvirus type 1 (EHV-1) infection is a major cause of pyrexias in winter among Japanese racehorses. In 2014–2015, the Japan Racing Association (JRA) changed the EHV-1 vaccine from an inactivated vaccine to a live vaccine (both produced by Nisseiken). To evaluate the effect of changing the vaccines, the capacities of these vaccines to induce virus-neutralizing (VN) antibodies were compared, and an epizootiological investigation of EHV-1 was performed at the JRA Ritto Training Center during epizootic periods from 2010–2011 to 2016–2017. Results Three-year-old horses that received the first dose of live vaccine showed higher geometric mean (GM) VN titers (205 and 220) than those that received inactivated vaccine (83, P
Databáze: Directory of Open Access Journals
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