Application of Y-STR, DIP-STR and SNP-STR Markers in Interpretation of Forensic Genetic Profiling: A Narrative Review

Autor:	Mehdi Forozesh, Shiva Irani, Azam Soleimani, Seyed Jalil Monabati
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Unbalanced mixed DNA Forensic genetic Marker Genetics Public aspects of medicine RA1-1270
Zdroj:	Iranian Journal of Public Health, Vol 51, Iss 7 (2022)
Druh dokumentu:	article
ISSN:	2251-6085 2251-6093
DOI:	10.18502/ijph.v51i7.10087
Popis:	Y-STR, DIP-STR, and SNP-STR are useful alternatives for testing the low quantity of DNA in solving the challenges in interpreting forensic genetic profiling. In an unbalanced mixed DNA, partial DNA is often not detected due to the effect of masking by the dominant DNA. Therefore, in such cases interpretation of the results is limited. Furthermore, profiling of these specimens cannot be performed using conventional forensic genetic methods. Biomarkers including Y-STR, DIP-STR and SNP-STR perform well in detecting DNA contributes in the mixed sample. In the present research, the performance of each is evaluated separately.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/118a787bc3664a52b2fdcdc0af22c022 Zobrazit plný text záznamu View record in DOAJ