Low prevalence of borderline oxacillin resistant Staphylococcus aureus (BORSA) in a tertiary care hospital in South Carolina

Autor: Connor Horne, Gabrielle DiMattia, Nicholas Perkins, Prerana Roth
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Infection Prevention in Practice, Vol 6, Iss 4, Pp 100414- (2024)
Druh dokumentu: article
ISSN: 2590-0889
DOI: 10.1016/j.infpip.2024.100414
Popis: Summary: Prompt treatment for Staphylococcus aureus bloodstream infections is often dependent on known diagnostic testing modalities to differentiate between methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). Borderline-oxacillin resistant S. aureus (BORSA), a rare, non-mecA mediated phenotype, has unclear resistance mechanisms but potentially significant consequences as it is frequently misidentified as MSSA but behaves more like MRSA. A retrospective analysis was performed of MSSA bloodstream infections to determine the prevalence of BORSA. Our institution found BORSA prevalence of 0.1%, consistent with literature. Though prevalence is low, due to unclear mechanisms and unreliable detection methods, BORSA may pose a therapeutic and epidemiological threat.
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