Absorption mechanism of three curcumin constituents through in situ intestinal perfusion method

Autor:	Y.-H. Wang, X.-M. Ke, C.-H. Zhang, R.-P. Yang
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Curcumin Demethoxycurcumin Bisdethoxycurcumin In situ intestinal perfusion Absorption mechanism Medicine (General) R5-920 Biology (General) QH301-705.5
Zdroj:	Brazilian Journal of Medical and Biological Research, Vol 50, Iss 11 (2017)
Druh dokumentu:	article
ISSN:	1414-431X 1414-431x
DOI:	10.1590/1414-431x20176353
Popis:	This study aimed to investigate the absorption mechanism of three curcumin constituents in rat small intestines. Self-emulsification was used to solubilize the three curcumin constituents, and the rat in situ intestinal perfusion method was used to study factors on drug absorption, including drug mass concentration, absorption site, and the different types and concentrations of absorption inhibitors. Within the scope of experimental concentrations, three curcumin constituents were absorbed in rat small intestines through the active transport mechanism.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/117c1803b1584b7284cc56602dde5228 Zobrazit plný text záznamu View record in DOAJ