| Autor: |
Ersin Cavus, Jan N. Schneider, Eleonora di Carluccio, Andreas Ziegler, Alena Haack, Francisco Ojeda, Celeste Chevalier, Charlotte Jahnke, Katharina A. Riedl, Ulf K. Radunski, Raphael Twerenbold, Paulus Kirchhof, Stefan Blankenberg, Gerhard Adam, Enver Tahir, Gunnar K. Lund, Kai Muellerleile |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 1, Pp 101008- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1097-6647 |
| DOI: |
10.1016/j.jocmr.2024.101008 |
| Popis: |
ABSTRACT: Background: The presence of myocardial scar is associated with poor prognosis in several underlying diseases. Late-gadolinium-enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging reveals clinically silent “unrecognized myocardial scar” (UMS), but the etiology of UMS often remains unclear. This population-based CMR study evaluated prevalence, localization, patterns, and risk factors of UMS. Methods: The study population consisted of 1064 consecutive Hamburg City Health Study participants without a history of coronary heart disease or myocarditis. UMS was assessed by standard-phase-sensitive-inversion-recovery LGE CMR. Results: Median age was 66 [quartiles 59, 71] years and 37% (388/1064) were females. UMS was detected in 244 (23%) participants. Twenty-five participants (10%) had ischemic, and 217 participants (89%) had non-ischemic scar patterns, predominantly involving the basal inferolateral left-ventricular (LV) myocardium (75%). Two participants (1%) had coincident ischemic and non-ischemic scar. The presence of any UMS was independently associated with LV ejection fraction (odds ratios (OR) per standard deviation (SD) 0.77 (confidence interval (CI) 0.65–0.90), p = 0.002) and LV mass (OR per SD 1.54 (CI 1.31–1.82), p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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