Análise do perfil de mães e crianças expostas intraútero ao HIV nascidas em uma maternidade de hospital público terciário do sul do Brasil

Autor: Nathalia Ventura Stefli, Luis Fernando Matoso Mendes, Andrea Maciel de Oliveira Rossoni, Tony Tannous Tahan, Betina Mendez Alcantara Gabardo, Tatiane Emi Hirose
Jazyk: English<br />Portuguese
Rok vydání: 2024
Předmět:
Zdroj: Residência Pediátrica, Vol 14, Iss 1 (2024)
Druh dokumentu: article
ISSN: 2236-6814
DOI: 10.25060/residpediatr-2024.v14n1-942
Popis: OBJECTIVES: evaluate the profile of children exposed intrauterine to HIV born in a tertiary hospital in southern Brazil, describe the prevalence of children classified as high risk and the rate of vertical transmission in this population. METODOLOGY: cross-sectional analytical-observational study. All HIV-exposed children born in 2019 and 2020 at the Clinical Hospital of the Federal University of Paraná were included. Data were collected from the hospitals operating systems, physical records and SISCEL. Study approved by the hospital ethics committee. RESULTS: 142 patients were included. Among the mothers, 26.06% had a detectable viral load in the last trimester, of which 54.05% were above 1000 copies; 37.32% were diagnosed during pregnancy; 40% of women who were diagnosed during pregnancy had a detectable viral load in the 3rd trimester (p=0.01). Of those who had a detectable viral load in the third trimester, 88.89% used ART irregularly or did not use (p < 0.01); 44.37% of newborns were classified as high risk by the current protocol in the period, while with the current new protocol would be 63.38%. The vertical transmission rate was 1.41%. There was 42.26% of loss of follow-up. CONCLUSION: the prevalence of vertical transmission was low, comparable to developed countries. Quality prenatal care, early diagnosis and adherence to ART are factors that modify the rates of vertical transmission of HIV due to the reduction of maternal viral load in the third trimester.
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