Epilepsy and quality of life: socio-demographic and clinical aspects, and psychiatric co-morbidity

Autor: Gloria Maria de Almeida Souza Tedrus, Lineu Correa Fonseca, Rachel Marin Carvalho
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Arquivos de Neuro-Psiquiatria, Vol 71, Iss 6, Pp 385-391 (2013)
Druh dokumentu: article
ISSN: 1678-4227
0004-282X
DOI: 10.1590/0004-282X20130044
Popis: Objective To study socio-demographic and clinical aspects, as well as psychiatric co-morbidity that influence the quality of life of adult epileptic patients. Methods One hundred and thirty-two individuals diagnosed with epilepsy were evaluated from neurological/clinical and psychiatric points of view and by the Quality of Life in Epilepsy Inventory (QOLIE-31). Predictive factors for the QOLIE-31 scores were studied. Results The regression analyses indicated the existence of psychiatric co-morbidity (total score, seizure worry, emotional well-being, energy/fatigue, social function and cognitive function) and a greater seizure frequency (total score, cognitive function and energy/fatigue) as predictive factors for lower scores in the total QOLIE-31 score and in various dimensions. Abnormalities in the neurological exam and poly-therapy with anti-epileptic drugs were negative factors limited to one of the dimensions cognitive function and social function, respectively. Conclusion The presence of psychiatric co-morbidity and a greater seizure frequency were the main factors influencing the quality of life in epileptic patients as evaluated by QOLIE-31.
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