| Autor: |
Siewert Stefan, Dierke Ariane, Stahnke Thomas, Großmann Swen, Brandt-Wunderlich Christoph, Supp Laura, Rosam Paula, Stiehm Michael, Bock Andrea, Zygmunt Marek, Schmitz Klaus-Peter |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Current Directions in Biomedical Engineering, Vol 9, Iss 1, Pp 587-590 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2364-5504 |
| DOI: |
10.1515/cdbme-2023-1147 |
| Popis: |
Fallopian tube occlusions represent one of the most common causes of female sterility. As an innovative treatment approach for affected persons, we previously presented the concept of a novel polymeric, self-expanding, and bioresorbable microstent. As a basis for microstent development, knowledge of the mechanical properties of the anatomical target structure represents a crucial requirement. The current work describes a methodological approach for the experimental determination of radial Fallopian tube compliance using optical coherence tomography. It could be shown that a quantitative assessment of the mechanical properties of porcine Fallopian tube samples - as a whole anatomical structure including the Tunica mucosa, the Tunica muscularis, and the Tunica serosa - is possible, using the described test setup. Future investigations on human samples will allow for valuable information regarding the structural-mechanical properties of the Fallopian tube. Therefore, the current work offers perspectives for the development of a novel gynecological microstent for the treatment of Fallopian tube occlusions. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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