Just a Tongue Anomaly or Something More?
| Autor: | Cristina Aguiar, Nuno Medeiros, Leandro Ribeiro, Artur Condé |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Gazeta Médica, Vol 1, Iss 1 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2183-8135 2184-0628 |
| Popis: | A 54-year-old woman with a past history of breast and uterine cancer, appeared at the Emergency Room with a six-month history of fatigue, weight loss (> 12 kg), lower limbs swelling and dysphagia due to progressive tongue enlargement. ENT examination demonstrated macroglossia (Fig. 1-A), that was confirmed by computed tomography (CT) scan (Fig. 1-B). Laboratory tests complemented with image findings showed the presence of a restrictive cardiomyopathy and a nephrotic syndrome. The abdominal fat biopsy with immunofixation electrophoresis was positive for light-chain amyloidosis. The patient began chemotherapy treatment with bortezomib, dexamethasone and cyclophosphamide, completing four cycles of treatment with frank tongue reduction. The patient died 5 months after the diagnosis.[...] |
| Databáze: | Directory of Open Access Journals |
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