Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates

Autor: Zongliang Chang, Weibing Qin, Huili Zheng, Kathleen Schegg, Lu Han, Xiaohua Liu, Yue Wang, Zhuqing Wang, Hayden McSwiggin, Hongying Peng, Shuiqiao Yuan, Jiabao Wu, Yongxia Wang, Shenghui Zhu, Yanjia Jiang, Hua Nie, Yuan Tang, Yu Zhou, Michael J. M. Hitchcock, Yunge Tang, Wei Yan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-21517-5
Popis: No male contraceptive pills are currently available. Here, the authors use triptonide, a compound derived from a Chinese plant, to deform sperm so that they cannot move properly, thereby causing reversible infertility in male mice and monkeys.
Databáze: Directory of Open Access Journals