Association of vitamin D deficiency and premature coronary artery disease
| Autor: | Hamidreza Norouzi, Naghmeh Ziaie, Mehrdad Saravi, Alireza Norouzi, Somayye Noei, Fazilat Jokar darzi, Fatemeh Norouzi, Maede Rajabi fumashi, Farbod Zahedi tajrishi, Shahram Norouzi |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Caspian Journal of Internal Medicine, Vol 10, Iss 1, Pp 80-85 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2008-6164 2008-6172 |
| Popis: | Background: Evidence suggests hypovitaminosis D is associated with increased risk of coronary artery disease (CAD) and its extent and related risk factors. However, some investigations have produced contrary results. Therefore, we aimed to evaluate the association between serum vitamin D levels and the severity of premature coronary artery involvement. Methods: This randomized prospective, case-control study was conducted in Babol from April 2013 to June 2017. We collected the demographic data and measured serum 25-OH-D levels of 294 patients (age≤50 years) diagnosed with CAD with coronary angiography as case group as well as 438 age and sex-matched controls. CAD severity was assessed using the Gensini score. Statistical analyses were used to assess the associations and p0.05). Conclusion: The results showed that the lower levels of vitamin D is associated with increased risk and extent of coronary artery involvement as well as some of the risk factors of CAD, including male gender, hypertension and positive family history for CVD. |
| Databáze: | Directory of Open Access Journals |
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