Gaps in hepatocellular carcinoma surveillance among insured patients with hepatitis B infection without cirrhosis in the United States

Autor: Mindie H. Nguyen, Lewis R. Roberts, Nicole M. Engel‐Nitz, Tim Bancroft, A. Burak Ozbay, Amit G. Singal
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Hepatology Communications, Vol 6, Iss 12, Pp 3443-3456 (2022)
Druh dokumentu: article
ISSN: 2471-254X
DOI: 10.1002/hep4.2087
Popis: Abstract Suboptimal adherence to guidelines for hepatocellular carcinoma (HCC) surveillance among high‐risk patients is a persistent problem with substantial detriment to patient outcomes. While patients cite cost as a barrier to surveillance receipt, the financial burden they experience due to surveillance has not been examined. We conducted a retrospective administrative claims study to assess HCC surveillance use and associated costs in a US cohort of insured patients without cirrhosis but with hepatitis B virus (HBV) infection, monitored in routine clinical practice. Of 6831 patients (1122 on antiviral treatment, 5709 untreated), only 39.3% and 51.3% had received any abdominal imaging after 6 and 12 months, respectively, and patients were up to date with HCC surveillance guidelines for only 28% of the follow‐up time. Completion of surveillance was substantially higher at 6 and 12 months among treated patients (51.7% and 69.6%, respectively) compared with untreated patients (36.9% and 47.6%, respectively) (p
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