Differentiating Arteriolosclerotic Ulcers of Martorell from Other Types of Leg Ulcers Based on Vascular Histomorphology

Autor: Julia Deinsberger, Jonas Brugger, Philipp Tschandl, Barbara Meier-Schiesser, Florian Anzengruber, Simon Bossart, Stanislava Tzaneva, Peter Petzelbauer, Kornelia Böhler, Helmut Beltraminelli, Jürg Hafner, Benedikt Weber
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Acta Dermato-Venereologica, Vol 101, Iss 5, p adv00449 (2021)
Druh dokumentu: article
ISSN: 0001-5555
1651-2057
00015555
DOI: 10.2340/00015555-3804
Popis: Clinical differential diagnosis of arteriolosclerotic ulcers of Martorell is challenging due to the lack of clearly affirmative instrument-based diagnostic criteria. The aim of this study was to develop vascular histomorphological diagnostic criteria differentiating Martorell ulcers from other types of leg ulcers. The histomorphology of patients diagnosed with arteriolosclerotic ulcers of Martorell (n = 67) was compared with that of patients with venous leg ulcers, necrotizing leukocytoclastic vasculitis, pyoderma gangrenosum, and non-ulcerative controls (n = 15 each). In a multivariable logistic regression model, the rates of arteriolar calcification (odds ratio (OR) 42.71, 95% confidence interval (CI) 7.43–443.96, p
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