Schistosoma mansoni: effects of anesthetics and antimonial drugs on worm shift in the mouse

Autor:	José Renan da Cunha-Melo, Paulo Marcos Z. Coelho
Jazyk:	angličtina
Rok vydání:	1986
Předmět:	Manson schistosomiasis Experimental disease in mice Antimonial drugs Worm shift Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216
Zdroj:	Revista do Instituto de Medicina Tropical de São Paulo, Vol 28, Iss 4, Pp 267-270 (1986)
Druh dokumentu:	article
ISSN:	1678-9946 0036-4665
DOI:	10.1590/S0036-46651986000400010
Popis:	Mice experimentally infected with Schistosoma mansoni were injected with sodium thiopental or sodium antimonyl gluconate (Triostib R), or submitted to halothane inhalation, with or without a previous injection of thiopental. Data obtained showed that halothane and thiopental induce worm shift to the liver (99 and 76%, respectively). Sodium gluconate and antimonium (Triostib R) shifted 52% of worms towards the liver. These results seem to indicate that the use of antimonium would be unnecessary, when surgical removal of schistosomules is carried out through the extracorporeal filtration technique, in patients with portal hypertension.
Databáze:	Directory of Open Access Journals
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