Innovative strategies for Lassa fever epidemic control: a groundbreaking study

Autor: Yasir Ramzan, Aziz Ullah Awan, Muhammad Ozair, Takasar Hussain, Rahimah Mahat
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: AIMS Mathematics, Vol 8, Iss 12, Pp 30790-30812 (2023)
Druh dokumentu: article
ISSN: 2473-6988
DOI: 10.3934/math.20231574?viewType=HTML
Popis: This study aims to develop a mathematical model for analyzing Lassa fever transmission dynamics and proposing effective control measures. The stability of the Lassa fever-free equilibrium point is examined and the model's accuracy is assessed using real-world data. Additionally, the parameter values and the basic reproduction number are estimated. A sensitivity analysis is also conducted, which identifies the key drivers influencing transmission dynamics. Moreover, the impact of model parameters on basic reproduction numbers is investigated. Multiple control methodologies including use of Ribavirin, implementing mobile health technology and incorporating natural predators are devised and analyzed using optimal control theory to curtail virus transmission.
Databáze: Directory of Open Access Journals