Síntese de 5-nitro-isatina e 5-cloro-isatina a partir da isonitrosoacetanilida Preparation of 5-nitroisatin and 5-chloroisatin from isonitrosoacetanilide

Autor: Bianca N. M. da Silva, Renato S. Bastos, Bárbara V. Silva, Angelo C. Pinto
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2010
Předmět:
Zdroj: Química Nova, Vol 33, Iss 10, Pp 2279-2282 (2010)
Druh dokumentu: article
ISSN: 0100-4042
1678-7064
DOI: 10.1590/S0100-40422010001000043
Popis: This article describes the preparation of 5-nitroisatin and of 5-chloroisatin from isonitrosoacetanilide in a single step, using readily available and inexpensive reagents. These reactions require around 90 minutes and may be carried out as an undergraduate experiment, providing an opportunity to discuss the electrophilic aromatic substitution mechanism, as well as spectroscopic techniques for product identification.
Databáze: Directory of Open Access Journals