| Autor: |
Linda J. Van Marter, MD, MPH, Page B. Pennell, MD, Carrie Brown, MS, Adam L. Hartman, MD, Ryan C. May, PhD, Thomas McElrath, MD, PhD, Dominic Ippolito, MS, Kimford J. Meador, MD, Anto Bagic, MD, Gregory Barkley, MD, Jennifer Cavitt, MD, Jennifer DeWolfe, MD, Jacqueline French, MD, Evan Gedzelman, MD, Elizabeth Gerard, MD, Sean Hwang, MD, Laura Kalayjian, MD, Gregory Krauss, MD, David Labiner, MD, Paul McCabe, MD, John Miller, MD, Alison Pack, MD, Patricia Penovich, MD, Maria Sam, MD, Enrique Serrano, MD, Suzanne Strickland, MD |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
The Journal of Pediatrics: X, Vol 7, Iss , Pp 100073- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2590-0420 |
| DOI: |
10.1016/j.ympdx.2021.100073 |
| Popis: |
Objective: To determine whether growth measures at birth differ between offspring of pregnant women with epilepsy and healthy pregnant women. Study design: The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study is a National Institutes of Health–funded, prospective, observational, multicenter investigation of pregnancy outcomes for mothers and their infants. Between 2012 and 2016, pregnant women with epilepsy and healthy pregnant women were enrolled at 20 US epilepsy centers. Pregnant women with epilepsy were exposed to various antiepileptic drugs. The main outcome measure was small for gestational age at birth. Principal univariate and multivariate analyses compared outcomes between pregnant women with epilepsy and healthy pregnant women. Secondary analyses focused on outcomes among mothers receiving different antiepileptic drug therapies. Results: In total, 345 infants were born to 331 pregnant women with epilepsy and 106 infants were born to 102 healthy pregnant women. No differences were seen between infants born to pregnant women with epilepsy vs healthy pregnant women in preterm births, major congenital malformations, 5-minute Apgar |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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