Detection of vaccine-derived poliovirus circulation by environmental surveillance in the absence of clinical cases

Autor: John Kofi Odoom, Evangeline Obodai, Gifty Boateng, Stanley Diamenu, Keren Attiku, Patrick Avevor, Ewurabena Duker, Bismarck Boahene, Miriam Eshun, Emmanuel Gberbie, Joseph Kwadwo Larbi Opare
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 2117-2124 (2021)
Druh dokumentu: article
ISSN: 2164-5515
2164-554X
21645515
DOI: 10.1080/21645515.2020.1852009
Popis: Background On August 25, 2019, the Noguchi Memorial Institute for Medical Research notified the confirmation of a circulating-vaccine-derived poliovirus type-2 (cVDPV2) from the Agbogbloshie environmental surveillance (AES) site, in the Greater Accra Region. A field investigation of the outbreak was conducted to describe the results of epidemiological and laboratory investigations, and control efforts. Methods We conducted a descriptive investigation, records review, and active-case-search. Caregivers were interviewed on the vaccination status of their children; knowledge, attitude, and practices on polio prevention; water, sanitation and hygiene practices, and health-seeking behaviors. Stool from healthy children
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