The Predictive Value of hsa_circ_0001313 (circCCDC66) in Egyptian Rectal Cancer Patients: A New Era in Precision Medicine

Autor:	Hend M. Batea, Safaa H. Mohy El-dine, Eman M. Kamha, Gehan M. Khedr, Ahmed Moaz, Doaa A. Abdelmonsif
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	circ_0001313 circular RNA rectal cancer gene expression response to nCRT Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Journal of Coloproctology, Vol 44, Iss 03, Pp e163-e170 (2024)
Druh dokumentu:	article
ISSN:	2237-9363 2317-6423 91598672
DOI:	10.1055/s-0044-1788602
Popis:	Introduction The involvement of circular RNAs (circRNAs) in cancer research has been emphasized in recent years due to evidence of their involvement in malignancy pathogenesis. Yet, the involvement of circRNAs in the resistance to cancer treatment remains to be clarified. Circular RNA 0001313 (circ_0001313) has a distinct expression in different cancers, and it is overexpressed in rectal cancer; hence, it could be a promising non-invasive stable biomarker and a therapeutic target for rectal cancer. Yet, its predictive role has not been studied in Egyptian rectal cancer patients.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/10dfdd88b2574e879d9b9159867283e8 Zobrazit plný text záznamu View record in DOAJ