Venous Thromboembolism Risk and Adherence to Pharmacological Thromboprophylaxis in Hospitalized Patients in Uruguay: First Nationwide Study

Autor: Valentina Mérola MD, Ana Carina Pizzarossa MD, MSc, Maynés López MD, Franco Peverelli MD, Gustavo Bruno MD, MSc, Mariana González MD, Federico Roca MD, Leticia Dentone MD, Gerardo Pérez MD, Lucía Da Silveira MD, Lilián Díaz MD, Josefina Tafuri MD, Rosario Cuadro MD, Martín Zaquiere MD, Guillermina Bartaburu MD, Franco Pacello MD, Carina Celio MD, María José López MD, Marcelo Viana MD, Laura Fraga MD, Valeria Blanco MD, Paula Chalart MD, Daniel Leal MD, Xilef Rodríguez MD, Laura Teti MD, Carolina Goñi MD, Eduardo Infante MD, Alejandra Prícoli MD, Victoria Altieri MD, Cecilia Guillermo MD, Rosario Martínez MD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical and Applied Thrombosis/Hemostasis, Vol 30 (2024)
Druh dokumentu: article
ISSN: 1938-2723
10760296
DOI: 10.1177/10760296241256368
Popis: Introduction Venous thromboembolism (VTE) is a serious, frequent, and preventable medical complication in hospitalized patients. Although the efficacy of prophylaxis (pharmacological and/or mechanical) has been demonstrated, compliance with prophylaxis is poor at international and national levels. Aim To determine the indication and use of pharmacological thromboprophylaxis in hospitalized patients in Uruguay. Methods An observational, descriptive, cross-sectional, multicentre study involving 31 nationwide healthcare facilities was conducted. Baseline characteristics associated with hospital admission, the percentage of the population with an indication for thromboprophylaxis, and the percentage of patients receiving pharmacological thromboprophylaxis were assessed. The VTE risk was determined using the Padua score for medical patients; the Caprini score for surgical patients; the Royal College of Obstetricians and Gynaecologists (RCOG) guidelines for pregnant-postpartum patients. Results 1925 patients were included, representing 26% of hospitalized patients in Uruguay. 71.9% of all patients were at risk of VTE. Of all patients at risk of VTE, 58.6% received pharmacological thromboprophylaxis. The reasons for not receiving thromboprophylaxis were prescribing omissions in 16.1% of cases, contraindication in 15.9% and 9.4% of patients were already anticoagulated for other reasons. Overall, just 68% of patients were “protected” against VTE. Recommendations of major thromboprophylaxis guidelines were followed in 70.1% of patients at risk. Conclusions Despite the progress made in adherence to thromboprophylaxis indications, nonadherence remains a problem, affecting one in six patients at risk of VTE in Uruguay
Databáze: Directory of Open Access Journals
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