Bone morphogenetic protein 1.3 inhibition decreases scar formation and supports cardiomyocyte survival after myocardial infarction

Autor:	Slobodan Vukicevic, Andrea Colliva, Vera Kufner, Valentina Martinelli, Silvia Moimas, Simone Vodret, Viktorija Rumenovic, Milan Milosevic, Boris Brkljacic, Diana Delic-Brkljacic, Ricardo Correa, Mauro Giacca, Manuel Maglione, Tatjana Bordukalo-Niksic, Ivo Dumic-Cule, Serena Zacchigna
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Science
Zdroj:	Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu:	article
ISSN:	2041-1723
DOI:	10.1038/s41467-021-27622-9
Popis:	Here the authors show that a monoclonal antibody against a soluble isoform of Bone Morphogenetic Protein 1 prevents cardiac cell death, reducing fibrosis and preserving cardiac function after myocardial ischemia.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/107372050a2b47219731ca9d8eaea059 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ