Feasibility of precision smoking treatment in a low-income community setting: results of a pilot randomized controlled trial in The Southern Community Cohort Study

Autor: Scott S. Lee, Nicole Senft Everson, Maureen Sanderson, Rebecca Selove, William J. Blot, Stephen King, Karen Gilliam, Suman Kundu, Mark Steinwandel, Sarah J. Sternlieb, Qiuyin Cai, Shaneda Warren Andersen, Debra L. Friedman, Erin Connors Kelly, Mary Kay Fadden, Matthew S. Freiberg, Quinn S. Wells, Juan Canedo, Rachel F. Tyndale, Robert P. Young, Raewyn J. Hopkins, Hilary A. Tindle
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Addiction Science & Clinical Practice, Vol 19, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 1940-0640
DOI: 10.1186/s13722-024-00441-1
Popis: Abstract Background The feasibility of precision smoking treatment in socioeconomically disadvantaged communities has not been studied. Methods Participants in the Southern Community Cohort Study who smoked daily were invited to join a pilot randomized controlled trial of three smoking cessation interventions: guideline-based care (GBC), GBC plus nicotine metabolism-informed care (MIC), and GBC plus counseling guided by a polygenic risk score (PRS) for lung cancer. Feasibility was assessed by rates of study enrollment, engagement, and retention, targeting > 70% for each. Using logistic regression, we also assessed whether feasibility varied by age, sex, race, income, education, and attitudes toward precision smoking treatment. Results Of 92 eligible individuals (79.3% Black; 68.2% with household income
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